Evolutionary Biology, Cell-cell Communication, and Complex DiseaseeBook - 2012
Even in this advanced age of genomics, the evolutionary processof unicellular and multicellular organisms is continually indebate. Evolutionary Biology, Cell-Cell Communication, andComplex Disease challenges current wisdom by using physiology topresent an integrative view of the nature, origins, and evolutionof fundamental biological systems.
Providing a deeper understanding of the way genes relate to thetraits of living organisms, this book offers useful informationapplying evolutionary biology, functional genomics, and cellcommunication studies to complex disease. Examining the 4.5billion-year evolution process from environment adaptations tocell-cell communication to communication of genetic information forreproduction, Evolutionary Biology hones in on the "why and how" ofevolution by uniquely focusing on the cell as the smallest unit ofbiologic structure and function.
Based on empirically derived data rather than associationstudies, Evolutionary Biology covers:
A model for forming testable hypotheses in complex diseasestudies
The integrating role played by the evolution of metabolism,especially lipid metabolism
The evolutionary continuum from development to homeostasis
Regeneration and aging mediated by signaling molecules
Ambitious and game-changing Evolutionary Biology suggests thatbiology began as a mechanism for reducing energy within the cell,defying the Second Law of Thermodynamics. An ideal text for thoseinterested in forward thinking scientific study, the insightspresented in Evolutionary Biology help practitioners effectivelycomprehend the evolutionary process.